| 1. | Progressive systemic sclerosis
进行性系统性硬化病 |
| 2. | There are dozens of symptoms of systemic sclerosis , and a huge variance in how people are affected by it
系统性硬皮病有许多种症状,在不同的人身上表现则有所不同。 |
| 3. | Systemic sclerosis ( ssc ) is a chronic autoimmune disorder marked by early skin lesions and the progressive tissue fibrosis
系统硬化是一种慢性自动免疫疾病，特征为早期皮肤损害以及进行性组织纤维化。 |
| 4. | Esophageal motility problems can occur in patients with progressive systemic sclerosis ( scleroderma ) because the submucosa becomes fibrotic
系统性硬化（硬皮病）病人食管蠕动障碍，因为黏膜下层纤维化。 |
| 5. | At low magnification , the collagen of the dermis is increased . chronic inflammatory cells are sparse with systemic sclerosis , unlike sle
低倍镜下，皮肤的胶原增加。不象sle病人,系统性硬化病人的慢性炎性细胞稀少 |
| 6. | Such fibrosis can occur anywhere in the gastrointestinal tract , but is most common in the lower esophagus , leading to the esophageal dysmotility with systemic sclerosis
这种纤维可发生在胃肠道的任何地方，但最常见于食管下端,导致系统性硬化病人食管蠕动障碍。 |
| 7. | At high magnification , the dermis is expanded by dense collagenous fibrosis in a patient with systemic sclerosis . immunofluorescence is not helpful with scleroderma
高倍镜下，系统性硬化症病人真皮中胶原纤维增加使皮肤增厚。免疫荧光检测对硬皮病是无用的。注意：近年来我们往往用系统性硬化症取代名词硬皮病。 |
| 8. | New york ( reuters health ) jan 17 - short - term treatment with the endothelin antagonist bosentan improes myocardial perfusion and function in patients with systemic sclerosis ( ssc ) , according to a report in the december 2006 issue of the journal of rheumatology
1月17日纽约（路透社健康报道） ：据《风湿学》杂志在2006年12月刊的一篇报道，短期给予内皮素拮抗剂波生坦可以改善系统性硬化患者的心肌灌注和心肌功能。 |
| 9. | New york ( reuters health ) jan 17 - short - term treatment with the endothelin antagonist bosentan improves myocardial perfusion and function in patients with systemic sclerosis ( ssc ) , according to a report in the december 2006 issue of the journal of rheumatology
1月17日纽约（路透社健康报道） ：据《风湿学》杂志在2006年12月刊的一篇报道，短期给予内皮素拮抗剂波生坦可以改善系统性硬化患者的心肌灌注和心肌功能。 |
| 10. | " the concept is that systemic sclerosis , which is a severe disease characterized by systemic fibrosis , is at the beginning mainly a vascular disease , and we hypothesize that using major vascular drugs ( calcium channel blockers , endothelin antagonists , prostacyclins , phosphodiesterase inhibitors , etc . ) from the beginning and at appropriate dosage may interfere with the fibrotic process which seems secondary , " dr
“从概念上讲，系统性硬化是一种以系统性的纤维化变性为特征的严重疾病，早期主要表现在血管性的病变，因此我们推测早期、适量地应用主要作用于血管的药物（如钙离子阻断剂，内皮素拮抗剂，前列环素，磷酸二酯酶抑制剂等）可能可以干预似乎是继发发生的纤维化过程。 ” |
